Evaluation of Diastolic Functions in Patients with Behcet ’ S Disease : a Tissue Doppler Study

Results: In conventional Doppler echocardiography, Mitral A-wave velocity and deceleration time were higher, and E/A ratio was lower in patients with BD (p=0.002, p=0.02, and p=0.006, respectively). Mitral E-wave velocity and isovolumetric relaxation time were comparable between groups (p>0.05). In TDI examination, E′/A′ ratio measured from lateral mitral annulus was lower, and A′ velocity measured from lateral tricuspid annulus was higher in patients with BD (p=0.03 and p=0.02, respectively). Other mitral annular TDI (E′, A′, S′, E/E′ ratio, and MPI) and tricuspid lateral annular parameters (S′, E′, E′/A′ ratio and MPI) were similar between two groups (p>0.05). In correlation analysis, lateral mitral annulus E′/A′ ratio were inversely correlated with disease duration in patients with BD (r = -0.54, p=0.002).